No.4 seed and last year's finalist Stefanos Tsitsipas rallied back from two-sets-to-love down for the third time of his career, battling past Lorenzo Musetti 5-7, 4-6, 6-2, 6-3, 6-2 in a first-round night-session showdown on Court Philippe-Chatrier in the early hours of Wednesday morning.
The Greek star, who squandered a two-sets-to-love lead against Novak Djokovic in the 2021 Roland-Garros final, next faces Czech qualifier Zdenek Kolar.
Musetti walks away from Paris on the back of a defeat from two-sets-to-love up for a second year in a row having blown a similar lead against Djokovic in the fourth round 12 months ago.