Another early exit for Angie
Over on Court 14, No.26 seed and former world No.1 Angelique Kerber crashed out of the first round 6-2, 6-4 to Ukrainian qualifier Anhelina Kalinina.
The German three-time major champion has now lost her opener in Paris five times in the last six years.
"I think I had a late start, especially I started to play better in the second set, but yeah, I don't know. I think she played good. I was not able to play my best tennis or like how I practiced in the last few days," said the 33-year-old Kerber.
"I think I have to accept that and looking forward to the next challenge."
Kalinina has yet to drop a set through four matches so far this week in Paris, having breezed through three qualifying rounds before advancing to the main-draw second round.
Spain's Paula Badosa, who won the Belgrade title a week ago, kept up her great form this season to ease past American Lauren Davis 6-2, 7-6(3).
Her compatriot and two-time Roland-Garros quarter-finalist Pablo Carreno Busta joined her in round two with a 6-3, 6-4, 6-3 triumph over Norbert Gombos of Slovakia.